| Titre | Année | Genre |
|---|---|---|
| Samurai Shodown | ???? | Baston |
| Sangokushi III | ???? | Stratégie |
| Schwarzschild | ???? | Stratégie |
| Secret of Monkey Island | ???? | Aventures |
| Sega Classics Arcade Collection | 1992 | Compilation |
| Sega Classics Arcade Collection | ???? | Compilation |
| Sengoku Densho | 1991 | Beat em up |
| Sensible Soccer | 1993 | Football |
| Sewer Shark | 1993 | Shoot em up |
| Shadow of the Beast 2 | ???? | Action |
| Shadowrun | 1996 | Aventures |
| Shining Force CD | ???? | RPG |
| Silky Lip | 1992 | RPG |
| Silpheed | ???? | Shoot em up |
| SimEarth | 1993 | Gestion |
| Sin Megami Tensei | ???? | RPG |
| Smurfs, The | ???? | Plate-forme |
| Snatcher | ???? | Aventures |
| Sol-Feace | ???? | Shoot em up |
| Sonic CD | ???? | Plate-forme |
| Soul Star | ???? | Shoot em up |
| Space Ace | ???? | Aventures |
| Spiderman vs. Kingpin | 1993 | Plate-forme |
| Star Wars - Rebel Assault | ???? | Shoot em up |
| Star Wars Chess | ???? | Echec |
| Starblade | 1994 | Tir |
| Stellar Fire | ???? | Shoot em up |
| Super League CD | 1993 | Baseball |
| Super Strike Trilogy | ???? | Compilation |
| Supreme Warrior | 1994 | Baston |
| Surgical Strike | 1995 | Tir |
| Switch | 1993 | Aventures |
| Syndicate | 1994 | Action |
